Cardiac Care
Cardiac Care
Cardiac Care
Redefining
Redefining
Redefining
beyond standard cardiology
beyond standard cardiology
beyond standard cardiology
We help providers uncover the biological drivers behind cardiovascular risk. Beyond reports, beyond markers, beyond events.
We help providers uncover the biological drivers behind cardiovascular risk. Beyond reports, beyond markers, beyond events.
We help providers uncover the biological drivers behind cardiovascular risk. Beyond reports, beyond markers, beyond events.
Working with Clinical and Scientific Partners
Working with Clinical and Scientific Partners
Working with Clinical and Scientific Partners
Developed alongside partners across healthcare, research, and technology to ensure the system reflects real-world clinical complexity.
Developed alongside partners across healthcare, research, and technology to ensure the system reflects real-world clinical complexity.
THE CORE PROBLEM
We treat Events.
But Disease begins earlier
Cardiology is built to respond once something goes wrong. But the biological drivers of disease begin long before they are even seen
Standard Approach
Treating Events
Event
Intervention
Follow-Up
A blockage was detected with a stent, followed up by a statin prescription; the patient later returned with a new lesion.
The WHY was never found because it was never visible
Vizzhy's Approach
Treating The Terrain
Terrain
Root Mechanism
Precision Action
The biological terrain reveals the upstream driver; a different intervention becomes possible.
This changes what you would do for the patient.
WHY YOUR BEST TEST STILL FAILS
You can measure more markers. You can run advanced panels. You can spend thousands. And still not know:
?
Why the disease formed?
?
Why is it progressing?
?
What will happen next?
Markers are not mechanisms.
Snapshots are not trajectories.
THE CORE PROBLEM
THE CORE PROBLEM
We treat Events.
But Disease begins earlier
We treat Events.
But Disease begins earlier
Cardiology is built to respond once something goes wrong.
But the biological drivers of disease begin long before they are even seen
Cardiology is built to respond once something goes wrong.
But the biological drivers of disease begin long before they are even seen
Standard Approach
Treating Events
Event
Intervention
Follow-Up
A blockage was detected with a stent, followed up by a statin prescription; the patient later returned with a new lesion.
A blockage was detected with a stent, followed up by a statin prescription; the patient later returned with a new lesion.
The WHY was never found because it was never visible
The WHY was never found because it was never visible
Vizzhy's Approach
Treating The Terrain
Terrain
Root Mechanism
Precision Action
The biological terrain reveals the upstream driver; a different intervention becomes possible.
The biological terrain reveals the upstream driver; a different intervention becomes possible.
This changes what you would do for the patient.
This changes what you would do for the patient.
WHY YOUR BEST TEST STILL FAILS
WHY YOUR BEST TEST STILL FAILS
You can measure more markers. You can run advanced panels. You can spend thousands. And still not know:
You can measure more markers. You can run advanced panels. You can spend thousands. And still not know:
?
Why the disease formed?
?
Why is it progressing?
?
What will happen next?
Markers are not mechanisms.
Snapshots are not trajectories.
Markers are not mechanisms.
Snapshots are not trajectories.
WHAT EACH APPROACH REVEALS
WHAT EACH APPROACH REVEALS
Standard Labs + Imaging
Standard Labs + Imaging
~5%
Genomics (Inherited Blueprint)
Genomics (Inherited Blueprint)
~16%
Gene Expression + Protein Activity
Gene Expression + Protein Activity
~42%
Metabolism + Epigenetics + Microbiome
Metabolism + Epigenetics + Microbiome
~68%
Vizzhy's Full Biological Terrain
Vizzhy's Full Biological Terrain
Vizzhy's Full Biological Terrain
100%
Vizzhy integrates measured and computed data across genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, microbiome, imaging, sensors and clinical records.
Vizzhy integrates measured and computed data across genomics, epigenomics, transcriptomics, proteomics, metabolomics, lipidomics, microbiome, imaging, sensors and clinical records.
HOW VIZZHY WORKS
HOW VIZZHY WORKS
HOW VIZZHY WORKS
We don't add more data.
We reveal missing causality.
We don't add more data.
We reveal missing causality.
We don't add more data.
We reveal missing causality.
Vizzhy reconstructs the patient's biology across multiple layers and computes
what is driving the disease.
Vizzhy reconstructs the patient's biology across multiple layers and computes what is driving the disease.
Vizzhy reconstructs the patient's biology across multiple layers and computes
what is driving the disease.
Measure
Measure
01
01
Multi-omics sample collection and laboratory analysis across genomics, proteomics, metabolomics, epigenomics, transcriptomics, microbiome and clinical data.
Compute
Compute
02
02
Cross-layer interrogation and terrain computation. The system identifies where biological layers agree, contradict or reveal mechanisms invisible to any single test.
Act
Act
03
03
Physician-facing clinical intelligence with precision drug assessment, care sequencing, nutrition and exercise guidance, and continuous monitoring. This changes decisions.
Biotwin:
Biotwin:
A computed model of the patient's current biology across multiple layers and computes what is driving the disease.
Hidden Mechanisms
Hidden Mechanisms
When different biological layers disagree, the disagreement often reveals the real disease mechanism, invisible to any single test.
Terrain State
Terrain State
Multiple health dimensions scored simultaneously, inflammatory burden, vascular integrity, metabolic reserve, mitochondrial function, coagulation balance.
Treatment Constraints
Treatment Constraints
Some patients carry persistent biological patterns that make standard therapies unsafe or ineffective. The BioTwin identifies them before prescribing.
The Depth behind a Single BioTwin
The Depth behind a Single BioTwin
The Depth behind a
Single BioTwin
A BioTwin brings together multiple biological layers to reveal what single tests cannot.It gives providers clearer visibility into hidden risks, enabling deeper and more confident decisions.
Vizzhy reconstructs the patient's biology across multiple layers and computes what is driving the disease.
A BioTwin brings together multiple biological layers to reveal what single tests cannot.It gives providers clearer visibility into hidden risks, enabling deeper and more confident decisions.
Genome
Genome
Genome
3.5B
3.5B
Base pairs
Base pairs
Methylation
Methylation
Methylation
850K
850K
Epigenetic sites
Epigenetic sites
Transcriptome
Transcriptome
Transcriptome
20K+
20K+
Gene expressions
Gene expressions
Mass-Spec Proteomics
Mass-Spec Proteomics
Mass-Spec Proteomics
9,285
9,285
Unique proteins
Unique proteins
IPP Proteomics
IPP Proteomics
IPP Proteomics
8,243
8,243
Proteins quantified
Proteins quantified
Metabolomics
Metabolomics
Metabolomics
500+
500+
Metabolites mapped
Metabolites mapped
Lipidomics
Lipidomics
Lipidomics
1,200+
1,200+
Glucose Datapoints
Glucose Datapoints
Gut Microbiome
Gut Microbiome
Gut Microbiome
6,476
6,476
Microbial species
Microbial species
Pathways
Pathways
Pathways
7,728
7,728
Protein-pathway links
Protein-pathway links
CGM
CGM
CGM
5,524
5,524
Glucose Datapoints
Glucose Datapoints
WHOOP
WHOOP
WHOOP
14 days
14 days
Continuous HRV + Sleep
Continuous HRV + Sleep
Clinical Labs
Clinical Labs
Clinical Labs
179
179
Glucose Biomarkers + Ranges
Glucose Biomarkers + Ranges
Glucose Biomarkers +
Ranges
Computed per Twin
Computed per Twin
Computed per Twin
Millions of biological data points integrated into one computed model
Millions of biological data points integrated into one computed model
12+
12+
Biological layers
Biological layers
9
9
Interface screens
Interface screens
THE PLATFORM
THE PLATFORM
THE PLATFORM
Clinical Cognition Interface
Clinical Cognition Interface
Clinical Cognition Interface
The BioTwin renders across a physician-facing clinical intelligence console. Physicians navigate a living biological model to understand why the disease is progressing and what to do next
The BioTwin renders across a physician-facing clinical intelligence console. Physicians navigate a living biological model to understand why the disease is progressing and what to do next
The BioTwin renders across a physician-facing clinical intelligence console. Physicians navigate a living biological model to understand why the disease is progressing and what to do next
Patient Summary
Patient Summary
Patient Summary
Phase, terrain overview, what matters now
Phase, terrain overview, what matters now
Cross-Layer Findings
Cross-Layer Findings
Cross-Layer Findings
Where biological layers agree or disagree
Where biological layers agree or disagree
Treatment Readiness
Treatment Readiness
Treatment Readiness
What is permitted, held or needs data
What is permitted, held or needs data
Trajectory
Trajectory
Trajectory
How fast each terrain dimension is changing
How fast each terrain dimension is changing
Precision Interventions
Precision Interventions
Precision Interventions
Drug assessment across biological layers
Drug assessment across biological layers
Biological Deep Dive
Biological Deep Dive
Biological Deep Dive
Layer-by-layer findings with evidence
Layer-by-layer findings with evidence
Imaging Integration
Imaging Integration
Imaging Integration
Structure vs biology coherence mapping
Structure vs biology coherence mapping
Continuous Monitoring
Continuous Monitoring
Continuous Monitoring
Sensor coupling, alerts, real-time
Sensor coupling, alerts, real-time
AI Clinical Reasoning
AI Clinical Reasoning
AI Clinical Reasoning
Physician Q&A with full biological context
Physician Q&A with full biological context
Not a report but
Not a report but
Not a report but
A Clinical Reasoning System
A Clinical Reasoning System
A Clinical Reasoning System
EXECUTION LAYER
EXECUTION LAYER
Execution Layers - Computed per patient
Execution Layers - Computed per patient
Execution Layers - Computed per patient
Rx
Rx
Precision Drug Layer
Precision Drug Layer
Multi-layer drug assessment, genomic safety gates, Pathway compatibility
Multi-layer drug assessment, genomic safety gates, Pathway compatibility
Multi-layer drug assessment, genomic safety gates, Pathway compatibility
Care
Care
Care Sequencing
Care Sequencing
Time-ordered plan. Upstream before downstream. Safety pacing.
Time-ordered plan. Upstream before downstream. Safety pacing.
Time-ordered plan. Upstream before downstream. Safety pacing.
Nutr
Nutr
Nutrition Guidance
Nutrition Guidance
Patient-specific constraints. Standard advice reversed where needed.
Patient-specific constraints. Standard advice reversed where needed.
Patient-specific constraints. Standard advice reversed where needed.
Move
Move
Exercise Safety
Exercise Safety
Pre-session safety checks. Intensity Limits. Escalation gates.
Pre-session safety checks. Intensity Limits. Escalation gates.
Pre-session safety checks. Intensity Limits. Escalation gates.
Sens
Sens
Sensor Monitoring
Sensor Monitoring
Continuous tracking. Cross-sensor coupling. Early warning signals.
Continuous tracking. Cross-sensor coupling. Early warning signals.
Continuous tracking. Cross-sensor coupling. Early warning signals.
FOR HOSPITALS
FOR HOSPITALS
FOR HOSPITALS
Why hospitals launch Vizzhy
Why hospitals launch Vizzhy
Why hospitals launch Vizzhy
Vizzhy integrates into existing cardiology workflows without EMR replacement. Delivered through a physician-facing designed for real clinical use.
Vizzhy integrates into existing cardiology workflows without EMR replacement. Delivered through a physician-facing designed for real clinical use.
Vizzhy integrates into existing cardiology workflows without EMR replacement. Delivered through a physician-facing designed for real clinical use.
Differential cardiology offering
Differential cardiology offering
Differential cardiology offering
Move beyond procedure-only economics. Launch a precision longitudinal care line that no competitor provides
Move beyond procedure-only economics. Launch a precision longitudinal care line that no competitor provides
Premium Preventive Program
Premium Preventive Program
Premium Preventive Program
High-value patients who want to understand their complete biology - not wait for an event. A new revenue layer built on deeper care.
High-value patients who want to understand their complete biology - not wait for an event. A new revenue layer built on deeper care.
No EMR dependancy
No EMR dependancy
No EMR dependancy
Vizzhy operates alongside existing systems. Samples collected locally, processed in certified labs. Results flow into a dedicated clinical interface.
Vizzhy operates alongside existing systems. Samples collected locally, processed in certified labs. Results flow into a dedicated clinical interface.
Address recurrence and residual risk
Address recurrence and residual risk
Address recurrence and residual risk
Identify hidden biological drivers behind unexplained progression, recurrent events, and residual inflammatory risk after optimal medical therapy.
Identify hidden biological drivers behind unexplained progression, recurrent events, and residual inflammatory risk after optimal medical therapy.
Strengthen physician trust
Strengthen physician trust
Strengthen physician trust
Give cardiologists tools that reveal what they have always suspected but never had the data to prove it. Better explanations. Better decisions.
Give cardiologists tools that reveal what they have always suspected but never had the data to prove it. Better explanations. Better decisions.
Global lab network
Global lab network
Global lab network
Multi-Omics analysis via established bio-banking protocols. Operational in the US and expanding internationally. India launch in progress.
Multi-Omics analysis via established bio-banking protocols. Operational in the US and expanding internationally. India launch in progress.
This is not adding complexity but
This is not adding complexity but
This is not adding complexity but
Removing Uncertainty
Removing Uncertainty
Removing Uncertainty
Start with a focused pilot
Start with a focused pilot
Start with a focused pilot
No long-term commitment required. See what Vizzhy reveals on your own patients before making any infrastructure decisions.
No long-term commitment required. See what Vizzhy reveals on your own patients before making any infrastructure decisions.
No long-term commitment required. See what Vizzhy reveals on your own patients before making any infrastructure decisions.
1
1
Select 10-25 cardiology patients
Select 10-25 cardiology patients
Select 10-25 cardiology patients
Post-stent, recurrent blockage, residual inflammation, unexplained progression - patients where your current approach has unanswered questions.
Post-stent, recurrent blockage, residual inflammation, unexplained progression - patients where your current approach has unanswered questions.
Post-stent, recurrent blockage, residual inflammation, unexplained progression - patients where your current approach has unanswered questions.
2
2
Collect samples and clinical data
Collect samples and clinical data
Collect samples and clinical data
Blood draw, stool sample, saliva. Combined with existing imaging and labs. No EMR integration required.
Blood draw, stool sample, saliva. Combined with existing imaging and labs. No EMR integration required.
Blood draw, stool sample, saliva. Combined with existing imaging and labs. No EMR integration required.
3
3
Vizzhy computes the BioTwin
Vizzhy computes the BioTwin
Vizzhy computes the BioTwin
Multi-Omics analysis in certified labs. Cross-layer terrain computation. Full biological model generated per patient.
Multi-Omics analysis in certified labs. Cross-layer terrain computation. Full biological model generated per patient.
Multi-Omics analysis in certified labs. Cross-layer terrain computation. Full biological model generated per patient.
4
4
Joint physician review
Joint physician review
Joint physician review
Your cardiologists review findings in the clinical intelligence interface. Side-by-side what standard care saw vs what Vizzhy revealed.
Your cardiologists review findings in the clinical intelligence interface. Side-by-side what standard care saw vs what Vizzhy revealed.
Your cardiologists review findings in the clinical intelligence interface. Side-by-side what standard care saw vs what Vizzhy revealed.
5
5
Evaluate and Decide
Evaluate and Decide
Evaluate and Decide
Did the BioTwin change the clinical picture? Did it reveal mechanisms your team would have not found? You decide the next step.
Did the BioTwin change the clinical picture? Did it reveal mechanisms your team would have not found? You decide the next step.
Did the BioTwin change the clinical picture? Did it reveal mechanisms your team would have not found? You decide the next step.
Every patient deserves care
based on their actual biology
Every patient deserves care
based on their actual biology
Every patient deserves care
based on their actual biology
Not a population average. Not a guideline approximation. Their actual biological terrain - measured, computed and clinically actionable
Not a population average. Not a guideline approximation. Their actual biological terrain - measured, computed and clinically actionable
Not a population average. Not a guideline approximation. Their actual biological terrain - measured, computed and clinically actionable
Austin, TX - Now expanding to India and beyond
Austin, TX - Now expanding to India and beyond
Austin, TX - Now expanding to India and beyond